Faculty
Ulka Sachdev-Ost, MD
Site Chief of Vascular Services, Magee-Womens Hospital of UPMC, Associate Professor, Surgery
Research Focus: Dr. Sachdev-Ost’s research has focused on the role of danger signaling, toll-like receptors (TLRs) and autophagy in regulating recovery from ischemic muscle injury. This work has potential implications in patients with peripheral vascular disease. Recently, she has also been studying growth and functional characteristics of muscle satellite cells that are harvested from patients with PAD, to determine whether they can be used in therapeutic applications. Finally, she is also studying the role of inflammation in patients with chronic venous insufficiency.
Yoel Sadovsky, MD
Executive Director, Magee-Womens Research Institute, Elsie Hilliard Hillman Chair of Women’s Health Research, Distinguished Professor of OBGYN, Microbiology and Molecular Genetics, Vice Chair of Research, Department of OBGYN and Reproductive Sciences, Associate Dean, Women's Health Research and Reproductive Sciences, University of Pittsburgh
Research Focus: Placental biology, seeking to decipher the molecular mechanisms underlying placental dysfunction, which impacts pregnancy and impedes fetal growth with devastating consequences to the mother and newborn
Melanie Scott, MD, PhD
Director of Graduate Education for Surgery Research, Associate Professor of Surgery
Research Focus: The role of the inflammasome and caspase-1 in trauma and hemorrhage
The role of the inflammasome and caspase-1 in sepsis
Inflammasome activation and metabolic control in the liver and during surgery
Sruti Shiva, PhD
Director, Nitric Oxide Metabolomics Core Facility, Co-Director, Center for Metabolic and Mitochondrial Medicine , Associate Professor of Chemical Biology/Pharmacology
Research Focus: Redox Biology
Signal Transduction
Translational Biomarkers
Biochemical and Molecular Pharmacology
Mark Shlomchik, MD, PhD
Professor and Chair, Immunology
Research Focus: B cell immune response and how the immune system is activated in systemic autoimmunity leading to pathogenesis
Sanjeev Shroff, PhD
Professor and Gerald E. McGinnis Chair in Bioengineering
Research Focus: Myocardial proteins and whole heart mechano-energetic function; Vascular stiffness and cardiovascular function; Large-scale mathematical models of biological systems
Thomas Smithgall, PhD
William S. McEllroy Professor of Biochemistry, Chair, Department of Microbiology and Molecular Genetics
Research Focus: Drug discovery and development targeting protein-tyrosine kinase signaling pathways in myeloid leukemia and HIV-1 accessory factors to combat AIDS.
Gwendolyn Sowa, MD, PhD
Tenured Professor and Chair of Physical Medicine & Rehabilitation , Co-Director of the Ferguson Laboratory for Orthopaedic and Spine Research at the University of Pittsburgh , Medical Director of the UPMC Total Care- Musculoskeletal Health Program
Research Focus: Active research program investigating the role of mechanical forces in disc degeneration
Richard Steinman, MD, PhD
Associate Dean, Director Medical Scientist Training Program
Research Focus: Cancer Pharmacology
Robert Sweet, MD
UPMC Professor of Psychiatric Neuroscience and Professor of Neurology, Director, Clinical Core, Alzheimer Disease Research Center, Director, T32, Training for Transformative Discovery in Psychiatry
Research Focus: Neurobiological mechanisms underlying the occurrence of psychotic symptoms, delusions and hallucinations