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Yannis Hadjiyannis, MD

    Education & Training

  • BSc – Molecular Genetics – The Ohio State University
  • Medical Research Scholars Program – National Institutes of Health
  • MD – The Ohio State University
  • Anatomic and Clinical Pathology Residency – University of Pittsburgh Medical Center
Research Summary

My primary focus will be the study and application regulatory dendritic cells (DCregs; also “tolerogenic DCs”), a novel cellular therapy for organ transplantation, ischemia, and autoimmunity. In this role, I will focus on generating and altering DCregs to improve their function. I will also oversee the use of various high-dimensional approaches such as RNAseq, multiplex immunofluorescence, and spatial transcriptomics to identify the impact of DCreg on the allograft microenvironment in several ongoing and completed clinical trials utilizing DCregs for liver and kidney transplantation

Career Goals

My overall career goal is to run an NIH-funded cell therapy lab at an academic medical center focused on the application of novel cell therapies for patients in need of transplantation or with refractory autoimmune disorders.