Skip to main content

Julia Leix, MD

    Education & Training

  • BS – Gannon University, Erie, PA
  • MD – Ross University School of Medicine  
  • Pediatric Residency – Lehigh Valley Reilly Children’s Hospital, Allentown, PA
  • Pediatric Hematology Oncology Fellowship – Children’s Hospital of Pittsburgh
Research Summary

Epigenetic mechanisms of tumorigenesis have been described in multiple mesenchymal tumors including bone sarcomas. In a recent study of 129 osteosarcoma samples, the Nacev laboratory identified a recurrent amplification of NCOR1.  This gene encodes a transcriptional co-repressor that forms a complex with the epigenetic regulator histone deacetylase 3 (HDAC3). NCOR1 amplification and the associated increase in NCOR1 protein could lead to dysregulated differentiation and transcriptional programs ultimately contributing to the pathogenesis of sarcoma.

Career Goals

My career goal is to become a successful physician-scientist in the field of pediatric hematology oncology. I am passionate and eager to participate directly in patient care as a pediatric oncologist as well as explore and develop new treatment modalities from  bench to the bedside. I am dedicated to becoming a physician-scientist with a translational focus.