Kevin P Mollen, MD

  • Samuel P. Harbison Assistant Professor of Surgery
  • Surgical Director, Inflammatory Bowel Disease Center, Children’s Hospital of Pittsburgh of UPMC
  • Scholar, R.K. Mellon Institute for Pediatric Research

Education & Training

  • Medical School – University of Buffalo School of Medicine – MD
  • Residency – University of Pittsburgh – General Surgery
  • Fellowship – Children’s Hospital of Pittsburgh of UPMC – Pediatric Surgery

Research Grants

NIH Grants:  K08, R03

Representative Publications

  1. Cunningham KE, Novak EA, Vincent G, Siow VS, Griffith BD, Ranganathan S,Rosengart MR, Piganelli JD, Mollen KP. Calcium/calmodulin-dependent proteinkinase IV (CaMKIV) activation contributes to the pathogenesis of experimental colitis via inhibition of intestinal epithelial cell proliferation. FASEB J. 2018Aug 16:fj201800535R. doi: 10.1096/fj.201800535R. [Epub ahead of print] PubMed PMID: 30113881.
  2. Melvin JE, Zuckerbraun NS, Nworgu CR, Mollen KP, Furtado AD, Manole MD. Management and Outcome of Pediatric Patients With Transient Small Bowel-Small Bowel Intussusception. Pediatr Emerg Care. 2018 May 5. doi: 10.1097/PEC.0000000000001503. [Epub ahead of print] PubMed PMID: 29746364.
  3. Emr BM, Alcamo AM, Carcillo JA, Aneja RK, Mollen KP. Pediatric Sepsis Update: How Are Children Different? Surg Infect (Larchmt). 2018 Feb/Mar;19(2):176-183. doi: 10.1089/sur.2017.316. Epub 2018 Feb 2. Review. PubMed PMID: 29394150.
  4. Siow VS, Bhatt R, Mollen KP. Management of acute severe ulcerative colitis in children. Semin Pediatr Surg. 2017 Dec;26(6):367-372. doi: 10.1053/j.sempedsurg.2017.10.006. Epub 2017 Oct 5. Review. PubMed PMID: 29126505.
  5. Coudriet GM, Delmastro-Greenwood MM, Previte DM, Marré ML, O'Connor EC, Novak EA, Vincent G, Mollen KP, Lee S, Dong HH, Piganelli JD. Treatment with a Catalytic Superoxide Dismutase (SOD) Mimetic Improves Liver Steatosis, Insulin Sensitivity, and Inflammation in Obesity-Induced Type 2 Diabetes. Antioxidants (Basel). 2017 Nov 1;6(4). pii: E85. doi: 10.3390/antiox6040085. PubMed PMID: 29104232; PubMed Central PMCID: PMC5745495.
  6. Cunningham KE, Okolo FC, Baker R, Mollen KP, Good M. Red blood cell transfusion in premature infants leads to worse necrotizing enterocolitis outcomes. J Surg Res. 2017 Jun 1;213:158-165. doi: 10.1016/j.jss.2017.02.029. Epub 2017 Feb 28. PubMed PMID: 28601308; PubMed Central PMCID: PMC5467453.
  7. Previte DM, O'Connor EC, Novak EA, Martins CP, Mollen KP, Piganelli JD. Reactive oxygen species are required for driving efficient and sustained aerobic glycolysis during CD4+ T cell activation. PLoS One. 2017 Apr 20;12(4):e0175549. doi: 10.1371/journal.pone.0175549. eCollection 2017. PubMed PMID: 28426686; PubMed Central PMCID: PMC5398529.
  8. Mazuski JE, Tessier JM, May AK, Sawyer RG, Nadler EP, Rosengart MR, Chang PK, O'Neill PJ, Mollen KP, Huston JM, Diaz JJ Jr, Prince JM. The Surgical Infection Society Revised Guidelines on the Management of Intra-Abdominal Infection. Surg Infect (Larchmt). 2017 Jan;18(1):1-76. doi: 10.1089/sur.2016.261. PubMed PMID: 28085573.
  9. Cunningham KE, Vincent G, Sodhi CP, Novak EA, Ranganathan S, Egan CE, Stolz DB, Rogers MB, Firek B, Morowitz MJ, Gittes GK, Zuckerbraun BS, Hackam DJ, Mollen KP. Peroxisome Proliferator-activated Receptor-γ Coactivator 1-α (PGC1α) Protects against Experimental Murine Colitis. J Biol Chem. 2016 May 6;291(19):10184-200. doi: 10.1074/jbc.M115.688812. Epub 2016 Mar 11. PubMed PMID: 26969166; PubMed Central PMCID: PMC4858969.
  10. Novak EA, Mollen KP. Mitochondrial dysfunction in inflammatory bowel disease. Front Cell Dev Biol. 2015 Oct 1;3:62. doi: 10.3389/fcell.2015.00062. eCollection  2015. Review. PubMed PMID: 26484345; PubMed Central PMCID: PMC4589667.