Education & Training
- Medical Degree – The Ohio State University – MD
- Residency – The Ohio State University - Pediatrics
- Fellowship – University of Texas Southwestern Medical Center – Pediatric Nephrology
NIH Grants: T32, R01
Dr. Bates studies the role of fibroblast growth factor receptors (Fgfrs) in kidney and lower urinary tract development. Through the use of genetically engineered mouse models, research in the Bates laboratory has identified how specific Fgfr family members and their docking proteins signal and function in renal and bladder development. He has generated many mouse models of renal dysplasia, cystic disease, and other congenital kidney and urinary tract anomalies. Recently his group has discovered novel roles for Fgfr2 in regulating the cell cycle in the context of bladder injury. Dr. Bates is the Program Director for one of only five T32 grants for pediatric nephrology fellowship training and Training Director for one of only a dozen Pediatrics Department K12 grants in the country. He is dedicated to mentoring trainees at all levels from medical students to junior faculty. The Bates laboratory is ideal for trainees with an interest in fundamental developmental processes that are impaired in congenital renal and urinary tract anomalies, e.g., trainees interested in Nephrology, Newborn Medicine or Urology or for trainees with an interest in Fgfr biology.
- Ikeda, Y, Zabbarova I, Schaefer CM, Bushnell DS, de Groat WC, Kanai AJ, and Bates CM. Fgfr2 is integral for bladder mesenchyme patterning and function. Am J Physiol Renal Physiol, 312(4): F607-F618, 2017. PMCID: PMC5407073.
- Puri P, Bushnell D, Schaefer CM, Bates CM. Six2creFrs2α knockout mice are a novel model of renal cystogenesis. Sci Rep, 6: 36736, 2016. PMCID: PMC5113122.
- Di Giovanni V, Walker KA, Bushnell D, Schaefer C, Sims-Lucas S, Puri P, Bates CM. Fibroblast growth factor receptor-Frs2 signaling Is critical for nephron progenitors. Dev Biol, 400(1): 82–93, 2015. PMCID: PMC4361332.
- Walker KA*, Sims-Lucas S*, Di Giovanni VE, Schaefer C, Sunseri WM, Novitskaya T, deCaestecker MP, Chen F, and Bates CM. Deletion of fibroblast growth factor receptor 2 from the peri-Wolffian duct stroma leads to ureteric induction abnormalities and vesicoureteral reflux. PLoS One. 18(2):e56062, 2013. PMCID: PMC3567073 (* authors contributed equally)